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Pr EP (pre-exposure prophylaxis) refers to an antiretroviral (ARV) drug that can be taken by an HIV negative person before potential HIV exposure to reduce risk of HIV infection.

While Pr EP for HIV prevention is a new approach to reduce HIV transmission, “prophylaxis” is not a new concept or practice.

Someone who expresses interest in Pr EP is also a good potential candidate.

The Centers for Disease Control and Prevention released guidelines in May 2014 that instruct clinicians on provision and management of Pr EP. Truvada as Pr EP is only available with a prescription.

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In July 2012, the United States Food and Drug Administration approved the ARV drug Truvada as Pr EP for uninfected individuals who are at high risk of HIV infection.

People who may be good candidates for Pr EP include those who can’t or don’t use male or female condoms regularly; don’t know the status of their partners, use drugs, or have been diagnosed with STIs; or exchange sex for money, food, or housing.

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